The tragic killing of Michael Brown on August 9, 2014, at the hand of Darren Wilson, a Ferguson, Missouri, police officer, further highlighted the long-standing disparities in health, education, employment, and overall well-being disproportionately burdening Black boys and young men in the St. Louis region (city and county). Since Brown’s death, we have observed a continuous environment of civil unrest and weakened confidence in the region’s welfare and economic future. An examination of reports and media discussions following the incidents in Ferguson reveal actions that have rightly centered on attending to structural determinants, racism, and equity (U.S. Department of Justice, 2015). Notably absent, however, was a central focus on the economic opportunity and overall well-being of Black boys and young men in the St. Louis region.